Wrinkles form perpendicular to muscles and can be reduced by inhibiting overactive muscles. Botox Cosmetic® (a controlled bacterial toxin) is a paralyzing agent injected directly into muscles to reduce muscle motion Botox works extremely well for horizontal forehead furrows, vertical lines between the eyebrows and "crow's feet" around the eyes. It is an minimally invasive office-based procedure with little to no downtime and lasts 3-4 months.